Aeromonas salmonicida toxin AexT has a Rho family GTPase-activating protein domain.
نویسندگان
چکیده
The N terminus of the Aeromonas salmonicida ADP-ribosylating toxin AexT displays in vitro GTPase-activating protein (GAP) activity for Rac1, CDC42, and RhoA. HeLa cells transfected with the AexT N terminus exhibit rounding and actin disordering. We propose that the Aeromonas salmonicida AexT toxin is a novel member of the growing family of bacterial RhoGAPs.
منابع مشابه
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ورودعنوان ژورنال:
- Journal of bacteriology
دوره 189 6 شماره
صفحات -
تاریخ انتشار 2007